Option 1
2 changesabout 12 hC$407 – C$495 (≈ US$11–14)El Castillo (Río San Juan)
San Carlos (Río San Juan)
Change in San Carlos (Río San Juan): you arrive at Muelle and the next bus leaves from Terminal. Take a taxi between terminals.
Managua
Change in Managua: the next bus leaves from the same terminal, Mayoreo.
Matagalpa